MICROBIO 160 Lecture Notes - Lecture 7: Oncogene, Mutation, Ct Scan

• School: UMASS-Amherst
• Department: Microbiology
• Course: MICROBIO 160
• Professor: Steven Goodwin

Document Summary

90% of cancer deaths occur because of where cancer ends up, not where it starts. The main reason cancer is so difficult to cure is because it can metastasize. The cancer growing where it began in the body is the . The cancer that has spread and started growing in another place is the . In order to spread, some primary cancer cells must break away, travel to another part of the body, and start growing there. Mutation of proto-oncogene creates an oncogene. Cells must penetrate boundary of extracellular matrix and survive unbound. Structural changes help release" cells from their neighbors. Ultimately these events are rare and improbable, but when they do happen the extracellular matrix and blood/lymph vessel walls. 1 proto-oncogene: a normal gene which, when altered by mutation, becomes an oncogene that can contribute to cancer. proto-oncogenes may have many different functions in the cell.