EHS 150 Lecture Notes - Lecture 5: Neural Tube Defect, Atrophic Gastritis, Megaloblastic Anemia
4 Jan 2017
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Document Summary
Folate in the diet: folate glutamate is the natural form 50% absorbed, folic acid is the form in supplements and fortified foods easily absorbed. Folate in the body: folate coenzymes are needed for. Transferring chemical groups containing a single carbon atom. Synthesis of dna important in tissues where cells are rapidly dividing. Recommended folate intake: unit: dietary folate equivalent (dfe) 1 dfe = 1 g of food folate or 0. 6 g of synthetic folic acid consumed with food or 0. 5 g of synthetic folic acid consumed without food: rdas: 400 g dfe/day for adult men and women. Food folate + 400 g synthetic folic acid for women of childbearing age. Needs are higher for infants and children. Folate and the risk of neural tube defects. Neural tube defects (ntd) such as spina bifida and anencephaly are caused by a combination of factors including low folate levels and a genetic predisposition.
