PHSL 3051 Lecture Notes - Lecture 23: Homeostasis, Sensory Neuron, Peripheral Chemoreceptors
Document Summary
Regulation of breathing in response to changes in blood pco2 and po2 and ph (h+) via negative feedback control. Increase in arterial blood pco2 stimulates the dorsal respiratory group. Central and peripheral chemoreceptors monitor blood gases and ph. Control networks in the brainstem regulate activity in somatic motor neurons leading to respiratory muscles. Receptors: central chemoreceptors in medulla/peripheral receptors in aortic and carotid bodies. Control center: dorsal respiratory group in medulla oblongata. Respiration neurons in the medulla control inspiratory and expiratory muscles. Neurons in the pons integrate sensory information and interact with medullary neurons to influence ventilation. Rhythmic breathing pattern arises from a neural network of spontaneous discharging neurons. Ventilation is subject to continuous modulation by chemo and mechanoreceptors. Medullary respiratory center in the medulla oblongata. Output to expiratory, some inspiratory, pharynx, larynx, and tongue muscles. Sensory receptors that respond to changes in the levels of certain chemicals in the body. Carotid body oxygen sensor releases neurotransmitter when po2 decreases.
