BSC1010C Lecture Notes - Lecture 8: Mitochondrion, Golgi Apparatus, Nuclear Membrane

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erinserval266

23 Sep 2016

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The endomembrane system: nuclear envelope has two lipid bilayers, not just one, the nuclear envelope is physically connected to the endoplasmic reticulum. Rough: has ribosomes imbedded in the er: where proteins attached to membrane are made. Smooth: no ribosomes imbedded: makes lipids and proteins for the er itself and for the plasma membrane. Ribosomes in the cytoplasm make proteins that will be in the cytoplasm: golgi apparatus: Also known as the golgi body or golgi complex. All the proteins and lipids made in the er that have to get out go through the. It attaches sugars to certain proteins and certain lipids. Some of the sugars are essential to the proper functioning of the lipid or protein or membrane. The golgi apparatus will sort the proteins and lipids as well. Outgoing transport vesicle: things ready to go out. Similar to the mitochondria because it has two membranes. Outer membrane and inner membrane with lots of folds.

Related Questions

1A. Which of the following statements about the endomembrane system is/are correct? (select all that apply)

A.	Secreted proteins are inserted into the ER as they are being made by ribosomes.
B.	the nucleus is surrounded by two phospholipid bilayers.
C.	"Free" ribosomes attach to the endoplasmic reticulum.
D.	Secreted proteins are moved from the ER to the Golgi by ribosomes

1B. Place these components of the endomembrane system into the correct order in respect to when they first function in the production of a secreted protein.

	Endoplasmic Recticulum (ER)
	Riibosome
	Nucleus
	Transport Vesicle
	Cell Membrane
	Golgi Apparatus

lilacgnat89

Complete the following sentences to examine various components of the endomembrane system.

Information within the ____________ is transcribed into mRNA and transported outside the nuclear envelope.

Proteins, which are synthesized by ____________ , are then released into the ____________ , where they are further folded and modified.

The ____________ does not have attached ____________ and produces lipids, such as steroids.

Once proteins are folded and modified, transport vehicles called ____________ pinch off and surround them with membranes to be transported elsewhere.

The vesicles are moved to the ____________ where they are sorted and packaged.

Transport vehicles called ____________ carry the macromolecules to the ____________ where they fuse and release their contents to the outside environment.

ribosomes

Golgi apparatus

smooth endoplasmic reticulum

vesicles

plasma membrane

rough endoplasmic reticulum

nucleus

secretory vesicles

1. The histones that form the core of the nucleosome get into the nucleus by which of the following?

a) Passive diffusion through nuclear pores

b) Selective and facilitated active transport through nuclear pores

c) Ribosomes located in the nucleus synthetize histones in the nucleus

d) Histones are made at the ER membrane and then diffuse to the nucleus

2. Membrane proteins that belong to the golgi, lysosome, or plasma membrane first pass through which organelle before reaching their final subcellular destination?

a) The golgi apparatus

b) The smooth ER

c) The nucleus

d) The ER membrane

e) The ER lumen

3. Where in the cell would a ribosomal protein be located if it has had its nuclear export signal inactivated (non-functional or non-existent).

a) The protein would be found in the ER lumen

b) The protein would remain in the nucleus

c) The protein would be secreted

d) The protein would remain in the cytoplasm

e) The protein would be in the ER membrane

4. Where would be the final destination of a protein if it contained a NLS anywhere in the protein sequence (and which is exposed to the cytoplasm after protein folding) but also contained an ER signal sequence at the carboxy terminus?

a) The ER lumen

b) The nucleus

c) The cytoplasm

d) The inner nuclear membrane

e) The ER membrane

5. The sequence K-D-E-L serves as a retention/retrieval signal for ER proteins.

a) True

b) False

6. The following are true for both cell membrane proteins and secretory proteins EXCEPT?

a) Precursors of the mature proteins contain signal sequence.

b) Both types of proteins contain stop-transfer sequences

c) Both types of proteins enter the ER while being synthetized

d) Both types of proteins pas through the golgi apparatus

e) Both are carried by clatherin-coated vesicles

7. If you isolate a regulated secreted protein from a secretory/storage vesicle and inject it into the cytosol, is will?

a) Be secreted through channels in the plasma membrane

b) Be taken up into secretory vesicle and secreted

c) Remain in the cytosol until it is degraded

d) Be taken up into the rough ER and follow the secretory pathway

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BSC1010C Lecture Notes - Lecture 8: Mitochondrion, Golgi Apparatus, Nuclear Membrane

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