BSC1010C Lecture Notes - Lecture 19: Atp Synthase, Oxidative Phosphorylation, Citric Acid Cycle

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26 Oct 2016
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Gen bio 19: nadh and fadh2 gets recycled into the etc in the mitochondria membrane, the hydrogen ions generate the atp through the atp synthase protein. Atp synthase allows the hydrogen to move down the gradient. No gradient means there is no more energy to make atp: etc function: to establish and maintain the hydrogen ion gradient. Total atp yield from prokaryotic aerobic respiration: substrate phosphorylation. 4 atp: net 2 from glycolysis, 2 atp from krebs cycle, oxidative phosphorylation. Re-oxidation of nadh: 22 from krebs cycle, re-oxidation of nadh and fadh2. Total yield: 4 + 34 = 38 (theoretical maximum, eukaryotic cells have theoretical maximum of 36, 2 atp spent crossing mitochondrial membrane. Chemiosmosis: diffusion of hydrogen ions across the membrane. What a(cid:271)out (cid:449)hen o(cid:454)(cid:455)gen isn"t a(cid:448)aila(cid:271)le: over 1 billion years there was life on earth with no o2. Lots of bacteria: they started capturing energy from sunlight and generating o2 as a byproduct.

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