CMD 377 Lecture Notes - Lecture 3: Blood Pressure, Autoregulation, Thrombosis

• School: URI
• Department: Communicative Disorders
• Course: CMD 377
• Professor: Kim Mikyong

Document Summary

Autoregulation: allows blood vessels to constrict in response to increased blood pressure and relax in response to decreased pressure. Metabolic mechanism: vessels dilate with increased co2 levels and constrict with decreased co2 levels. Perfusion pressure: normal blood pressure in the brain, difference b/w arterial, intracranial (csf), and venous pressure allows blood to circulate. Hypoperfusion pressure: no pressure difference b/w the 3 systems, causes decreased in the circulation of blood, distal branches of the 3 cerebral arteries are affected, water shed lesions occur, causes diffuse sign behaviorally. Ischemic strokes: caused by sudden vascular insufficiency: thrombosis. Generally caused by occlusion of blood vessels at the site. Typically caused by atherosclerosis (plaque build-up: embolism. The embolus is moved to the distant part of body and gets lodged. Behavioral signs are similar to thrombosis: transient ischemic attack (tia) Deficits persist for only a few minutes to hours. Often caused by minute emboli which become broken down: intracerebral hemorrhage.