CMD 377 Lecture Notes - Lecture 12: Superior Cerebellar Peduncle, Middle Cerebellar Peduncle, Flocculonodular Lobe

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Anatomy and function major fissures and lobes. Posterolateral fissure: separates the flocculonodular lobe from the body of the cerebellum. Flocculonodular lobe: medial portion (nodulus) and lateral portion (flocculus, involved in the maintenance of equilibrium and coordination of eye movement. Primary fissure: separates the anterior and posterior lobe. Vermis: the most medial zone, involved in the regulation of posture (trunk) and of muscle tone and posture during stereotypes movements. Intermediate zone (paravermal zone: adjacent to the vermis in each hemisphere, involved in the regulation of posture (distal muscles) and correction of muscles. Lateral zone: involved in the planning and coordination of voluntary movements (learned, skillful movements) Lesion of the vermal or paravermal zone: results in the anterior lobe syndrome which primarily affects the legs (ataxia) causes postural instability. Lesion of the lateral hemisphere: results in the neocerebellar syndrome, effects all ipsilateral to the side of the lesion. Lesion of the flocculonodular lobe: results in abnormal eye movement and loss of equilibrium.

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