BISC 104Lxg Lecture Notes - Lecture 12: Peripheral Nervous System, Codeine, Anandamide
1 Mar 2017
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Document Summary
Most widely used illegal drug in the united states. Principal psychoactive ingredient in the leaves, flowers, and stems is thc. Binds to receptors (endocannabinoid receptors) in brain regions involved in thinking, memory, and motor control. One neurotransmitter that normally binds to the receptors is anandamide (brains own thc) May regulate mood, memory, pain, appetite, and movement. Interferes with reuptake of dopamine - rush of intense pleasure, self-confidence and power. Increases effects of norepinephrine - body goes into emergency mode. Synthetically produced stimulants that closely resemble dopamine and norepinephrine. Effects: cause user to feel exhilarated and confident, suppress appetite and need for sleep. In peripheral nervous system, increases heart rate and blood pressure. In cns, facilitates release of dopamine and serotonin, creating pleasurable feelings of relaxation. Natural or synthetic drugs that are medically important but have high potential for abuse. Mode of action: opiates bind to receptors of the body s natural opiates.
