BISC 220Lg Lecture Notes - Lecture 4: Complement Membrane Attack Complex, Immunoglobulin A, Antigen

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Cells are going cancerous all the time (dna replication errors that cuase mutatin and then cancer) Autoimmune diseases = immune systems attack normal tissues as well as foreign cells (ms) Innate: nonspecific are inherited and fully active at birth; active, no memory. Acquired: specific, adaptive (learned and not inherited), need time to turn on involving mitosis; inactive until you activate them, when active, much more powerful and do have memory. Both work on same threats but have different timescale. Extra fluid gets collected in series of blind ended lymph capillaries. Force causing lymph to enter: pressure gradient that comes form muscular pumping (skeletal muscles form the pump) Pumping pulls water out of lymph nodes? (upper right) In the tissue are gigantic number of lymphocytes t and b (specific immune defense) B cells: fully activated when receive stimulus from helper t cell. Activation for b cell is dangerous thing: can cause autoimmune disease.

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