BIO 337 Lecture Notes - Lecture 1: Edgar Adrian, Slow-Wave Sleep, Delta Wave
Document Summary
Hypnos (god of sleep) and thanatos (death) - greek mythology (sons of erebus (darkness) and nyx (night)) Sir charles sherrington w/ edgar douglas adrian - discoveries regarding the function of neurons. Hour of deep sleep - no nerve activity. Old viewpoint - sleep is dispensable - death-like understanding of sleep phenotype. Sleep - actively generated (have to be put to sleep via mechanisms) & is a composite physiological state (as complex as the state of wakefulness) Electroencephalogram (eeg) - electrodes attached to the surface of the scalp in different configurations) to record integrated cerebral cortical activity (electrical) Spectral analysis - ridges aren"t rigidly defined. Drowsy - wavelengths start to slow - alpha waves. Stage 2 - sleep spindles (bursts of activity) and k complexes (large voltage spikes) Rem (rapid-eye-movement) sleep - low-voltage (looks like the person is awake), random, fast w/ sawtooth waves. Paralyzed (no muscle tone - actively inhibited)
