ANSC 330 Lecture Notes - Lecture 6: Hindgut Fermentation, Lactose Intolerance, Sucrose Intolerance
Document Summary
Major carbohydrate found in milk: 5% of milk is lactose, whey protein concentrate is 40% lactose. Disaccharide composed of a glucose and galactose unit connected by a beta-glycosidic bond: bond is cleaved by the enzyme lactase. Liberates free glucose and galactose monosaccharides: lactose digestion. Non-ruminants: occurs in the si along the brush border membrane by lactase. Ruminants: pre-ruminant calves, lambs, kids, suckling reflex causes alignment of the esophageal groove. Causes milk flow directly to the abomasum during suckling, bypassing fermentation. Digested similarly to non-ruminants: ruminants with a functional rumen, undergoes ruminal fermentation, what isn"t fermented is digested in the si by lactase, lactase. Only produced by mammals: produced by enterocytes of the si, high levels in neonatal and young animals, diet consists primarily of milk. Insufficient lactase is called lactose intolerance which occurs in the hindgut fermentation and disruption of osmotic balance.
