HNFE 1004 Lecture Notes - Lecture 5: Blurred Vision, Cardiovascular Disease, Reactive Hypoglycemia

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Type 1 (genetics) and type 2 (obesity) Before we knew how to treat it. Greek words for siphon (d) and sweet (m) Patients have a problem with regulating blood glucose (sugar) Normally it is tightly regulated by hormones. Pancreas is an exocrine and an endocrine gland. Pancreas secretes insulin in response to increased blood sugar. Stimulates cells (in muscles) to take up glucose from the blood. Promotes extra glucose to fat in liver and adipose tissue. Pancreas secretes glucagon in response to decreased blood sugar. Stimulates liver to release glucose into the blood. Muscle and adipose tissue cannot take up glucose. Body cannot use glucose and becomes malnourished. In history, tasted the urine to test for diabetes. Used as energy source instead of muscle protein. Converted to ketone bodies in the liver. Injections discovered in 1921 by dr. banting who injected it into dogs after removing the pancreas.

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