HNFE 1114 Lecture Notes - Lecture 12: Thiamine, B Vitamins, Micronutrient

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B vitamins: team players for carbs: micronutrient, water soluble, absorbed in blood, never toxic thru food, toxicity in supplements- because of where they are stored in body. Vitamin b1: thiamin: coenzyme in glycolysis, synthesis of neurotransmitters, synthesis of ribose and deoxyribose (parts of rna and dna, needed for muscle function, low toxicity- easy to excrete. In us and globally: alcohol interferes with body"s absorption of b1, increases excretion. Wernicke- korsakoff syndrome- no alcohol system, but looks like drunk; slurred speech, difficulty with cognition, eyes are unable to focus. Deficiency is rare in us: poor healing and replication of cells, cracked corners of mouth, red tongue, rash. Toxicity rare: increase excretion but bright fluorescent yellow urine. Milk isn"t sold in clear plastic because the light degrades it, the riboflavin starts to degrade in light. Coenzyme in glucose, fatty acids, and cholesterol metabolism. Dementia- forgetting where people are going, forgetting loved ones.

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