BIOB10H3 Lecture Notes - Lecture 9: Lysosome, Hydrolase, Endosome
Document Summary
Lysosomes: destined for lysosomes, immediate delivery to cell surface (exocytosis, destined for secretory vesicles (exocytosis) Lysosomes: membrane enclosed organelles with digestive enzymes, such as, proteases, nucleases: digest macromolecules, all these enzymes are acid hydrolases. Acid hydrolases: add an acidic ph, allowing the lysosomes to maintain a ph of. 4. 5-5 (acidic: note, cytosol has a ph of 7. 2. Destructive enzymes are prevented from running out of control by: being kept in a membrane enclosed organelle (not in the open where they can destroy everything) If they do break out, the ph of the cytosol (7. 2) is not where they want to perform. Once digested (i. e. destroyed) in the lysosome, the final products are chopped up and carried to the cytosol where the cell can reuse of excrete them. Late endosomes fuse with the lysosome to form an endolysosome: the late endosome can also fuse with the endolysosome.
