BIO 1140 Lecture Notes - Lecture 11: Metabolic Pathway, Cellular Respiration, Isoleucine
Document Summary
Chemical chaos would result if a cell"s metabolic pathway were not tightly regulated. A cell regulates its metabolism by switching on or off genes that encode specific enzymes. At diff, temp and ph, enzyme change shape and may not function as effectively. Production of molecules that inhibit or promote enzyme function. Some enzymes require or more cofactors or coenzymes to function. Cofactors are inorganic ions, i. e. fe++, mg++, zn++ Coenzymes are organic molecules including atp, nadh, and vitamins. These molecules are provided primarily from the diet. Have a similar shape to the substrates and compete with the substrates fro the active site. Bind to the enzyme at a different location, changing the conformation of the active site and thereby changing the reaction rate. Modify the active site of the enzyme so that substrate binding is reduced or prevented. Modify the active site of the enzyme so that the affinity of the substrate increases.
