CHM-233 Lecture Notes - Azobenzene, Naproxen, Paracetamol
Document Summary
A mixture of two compounds, syn- and anti- azobenzene was separated using different solvent mixture as the mobile phase by means of tlc technique in order to test what solvent separated the mixture better. Additionally, an unknown analgesic was analyzed with tlc with the purpose of identifying the presence of acetaminophen, caffeine, or naproxen. As general results the best solvent was 90:10 hexane ethanol and the unknown showed presence of all three: acetaminophen, naproxen and caffein. Regarding the analgesic analysis, the unknown identified as 306 c tested positive for the presence of all three compounds caffeine, naproxen, acetaminophen. The resulting rf values for these three compounds and the markers were determined to be the same, 0. 131, 0. 383 and 0. 498 respectively. Figure 1: tlc of azobenzene using 3 different solvents. Figure 2: tlc of an unknown to identify its components. Caffeine rf = 0. 616cm / 4. 7 = 0. 131.
