Lecture : Stress and Disease Textbook Notes
Document Summary
An examination with no physical stressor may elicit a reactive response. Assumes that immune-mediated diseases result from complex interrelationships among psychosocial, emotional, genetic, neurological, endocrine, Stress overview: allostasis, multiple mediators, and systems: increased knowledge of the link between stress and disease is supported by the concept of allostasis - the process by which the body responds to stressors in order to regain homeostasis. Differs from the "fixed homeostasis model" in which physiological regulation revolves around an unchanging set point. When we experience allostatic overload, this load exacts a wear and tear toll on our bodies. Because the brain is a key pla yer in perceiving stress, Regulation of the hypothalamic-pituitary-adrenal system: a key stress hormone relationship is the regulation of the hypothalamic-pituitary-adrenal (hpa) system pituitary cells that, in turn produce adrenocorticotropic hormone (acth) The perception of stress activates the hypothalamus to secrete corticotropin-releasing hormone (crh), which binds to specific receptors on anterior.