What can you find out about SNP: rs1136201
Useful links: https://www.pharmgkb.org/ http://www.ncbi.nlm.nih.gov/genome/
6) Compare the amino acid sequence of the reference gene and the gene containing the SNP. Give the sequence of the two amino acids flanking the mutation site. Example: reference sequence: Xxx-Yyy-Zzz; SNP sequence: XxxAaa-Zzz
7) Is the gene associated with an FDA label genomic warning?
8) What does the warning require to be done?
9) Which two FDA approved therapeutic antibodies target the gene?
10)Does the rs1136201 SNP change the therapeutic response of the patient to treatment?
11)Does the rs1136201 SNP influence side effects, risks or adverse effect in patients?
12)Give the PMID of a paper to support your answer (reference)
13)Give the full citation of the journal article identified in (12)
What can you find out about SNP: rs1136201
Useful links: https://www.pharmgkb.org/ http://www.ncbi.nlm.nih.gov/genome/
6) Compare the amino acid sequence of the reference gene and the gene containing the SNP. Give the sequence of the two amino acids flanking the mutation site. Example: reference sequence: Xxx-Yyy-Zzz; SNP sequence: XxxAaa-Zzz
7) Is the gene associated with an FDA label genomic warning?
8) What does the warning require to be done?
9) Which two FDA approved therapeutic antibodies target the gene?
10)Does the rs1136201 SNP change the therapeutic response of the patient to treatment?
11)Does the rs1136201 SNP influence side effects, risks or adverse effect in patients?
12)Give the PMID of a paper to support your answer (reference)
13)Give the full citation of the journal article identified in (12)