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18 Mar 2018

3. Suppose the recombination (crossing-over) frequencies between two specific genes on the same chromosome are listed below:

Gene 1

Gene 2

Recombination frequency

mol-1

bio-3

12%

mol-1

gen-4

19%

gen-4

bio-3

8%



Which two genes are closest together? What is the order of the genes?

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Elin Hessel
Elin HesselLv2
19 Mar 2018

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Related questions

My textbook says that the average length of a human chromosome is 140 cM (centimorgans). But how is it possible? I mean, since a frequency of recombination of 1 % indicates that two genes are separated by a distance of 1 cM, if we consider a gene in the 3' extremity of a chromosome and another gene in the 5' extremity of the same chromosome, their frequency of recombination should be 140%! What am I doing wrong?

1) An individual is heterozygous for 3 genes (A/a B/b and C/c). He is crossed to an individual that is homozygous recessive for the same 3 genes (a/a b/b and c/c). The following offspring were seen. Which of the following phenotypes represent a double crossover event? (Hint - are you seeing all of the phenotypes in the next generation that you expected to see?) Select all that apply.

Phenotype Number

+++

154

+b+

322

a+c

318

abc

148

++c

76

ab+

82

2) Use the same information in the question above. What is the gene order?

The gene order is B-C-A

The gene order is A-B-C

The gene order is B-A-C

3) Using the same information as in the previous problem, What is the recombination frequency between each gene pair? Round your answer to 2 decimal places. For example, report 12.2345% as 0.12.

recombination frequency between A/B =

recombination frequency between A/C =

recombination frequency between B/C =

******According to the hint, we don't see two phenotypes that we are expecting which are +bc, and a++. Are those the ones that represent double crossovers, and if so, how do we calculate the recombination frequency between each gene? Would very much appreciate some help.

Which of the following statements is true? Select one:

a. The closer two genes are on a chromosome, the lower theprobability that a crossover will occur between them. b. Theobserved frequency of recombination of two genes that are far apartfrom each other has a maximum value of 100%.

c. All of the traits that Mendel studiedseed color, pod shape,flower color, and othersare due to genes linked on the samechromosome.

d. Linked genes are found on different chromosomes.

e. Crossing over occurs during prophase II of meiosis.

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