Can some please explain how unsaturated fatty acid affect insulin resistance and how saturated fatty acids affect insulin resistance. Can you please explain in detail the mechanism involved in this :)

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Keith LeannonLv2

24 Mar 2018

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Related questions

1) In your own words, what does it mean for a given cell/tissue to be 'insulin resistant'?

2) For each tissue/organ listed, state one feature (e.g. 'increased lipogenesis') that you would expect to find in the tissue/organ were insulin resistant:

Liver, Adipose tissue, skeletal muscle

3) Briefly identify the factor which is obesity that can cause insulin resistance and briefly explain the molecular mechanism.

If a cell is placed in a cooler environment, the fluidity of the membrane can decrease. Would the cell increase the amount of saturated or unsaturated fatty acids in the phospholipid bilayer to restore the normal level of fluidity? Explain your answer.

maroonduck208

The table below shows the percent of each type of phospholipid fatty acid tail found in each type of the grass membranes on Oct. 2 and Dec. 8th. The first column in the table shows the length of the fatty acid tail and the number of double-bonds in the fatty acid. For example the fatty acid â16:0â would be a fatty acid that was 16 carbons long and had 0 double-bonds. The second and third columns show the percent of all phospholipid fatty acids that were of this type. For example, in grass collected on October 2nd, 23.9 % of the phospholipid fatty acids were 16 carbons long and had no double-bonds (16:0 type), and in the grass collected on Dec. 8^th, 21.0 % of the phospholipid fatty acids were 16 carbons long and had no double-bonds (16:0 type).

Fatty Acid composition of Phospholipids	October 2	December 8
Fatty Acid composition of Phospholipids	% of phospholipids	% of phospholipids
16:0	23.9	21.0
16.1	0.4	0.7
18:0	0.8	0.4
18:1	9.6	6.1
18:2	34.4	38.6
18:3	30.2	32.4
20:0	0.7	0.7

A. For each date the grass was collected, calculate the total percent of phospholipid fatty acids that were saturated fatty acids and the total percent of phospholipid fatty acids that were unsaturated fatty acids.

B. Draw a column graph that shows the total percent of phospholipid fatty acids that were saturated for each date that grass was collected and the total percent of phospholipids that were unsaturated for each date that grass were collected.

C. Why are the % of saturated and unsaturated fatty acid tails on the phospholipids of the Oct 2^nd collected grass and the Dec 8^th collected grass not the same? Use your understanding of membrane fluidity to address why these percentages have changed during this time period.

D. During this experiment the concentration of cholesterol found in the membranes of the grass was also measured. On Oct. 2^th the concentration of cholesterol was 1.10 umol/mg and on Dec. 8^th the concentration of cholesterol was 1.22 umol/mg. Why did the concentration of cholesterol change? Use your understanding of membrane fluidity to address why these concentrations have changed during this time period.