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Genes a, b and c are recessive. Females heterozygous at these three loci were crossed to phenotypically abc males. The numbers of progeny recovered in each phenotypic class are shown below (+ represents the wild-type allele of each locus):

+ + + 13

a b c 10

+ + c 58

+ b + 0

a + + 424

a b + 67

a + c 1

+ b c 427

A) What is the order of the three genes?

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Jamar Ferry
Jamar FerryLv2
28 Sep 2019

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Related questions

Drosophila females heterozygous for three recessive X-linkedmarkers, y (yellow body), ct (cut wings), and m (miniature wings),and their wild-type alleles were crossed to y ct m males. Thefollowing progeny were obtained:

1 YELLOW, CUT, MINIATURE = 30.

2. Wild-type = 33

3. yellow = 10

4. cut, miniature = 12

5. miniature = 8

6. yellow, cut = 5

7 yellow miniature = 1

8. cut = 1

1. Determine the order of these genes

2. Calculate the map distances between the genes

3.determine the coefficient of coincidence and the interferenceamong these genes

Drosophila has four pairs of chromosomes: the sex chromosomes (XX in the females; XY in the males) and three pairs of autosomes. You are studying a new mutant strain with blue eyes. You wish to know if blue eye colour is a dominant mutation and on which chromosome the blue eye locus can be found. When you cross a pure-breeding female blue-eyed fly with vestigial wings and spineless bristles to a male fly with wild type eye colour, wings, and bristles, all of the F1 progeny are completely wild type. An F1 male is backcrossed to a triple mutant female, producing the following progeny (remember that there is no crossing over in Drosophila males):

Wild type eyes, wings, and bristles:

72 females, 69 males

Wild type eyes and bristles, vestigial:

83 females, 77 males

Wild type wings, blue eyes, spineless:

60 females, 65 males

Blue eyes, spineless, vestigial:

62 females, 58 males

a. Is the mutation dominant or recessive? Explain.

b. Since you know that the locus for vestigial wings is on chromosome 2 and the locus for spineless bristles is on chromosome 3, what chromosome carries the locus for blue eyes? Show your work, including the step-by-step reasoning you used to arrive at your answer.

c. When an F1 female is backcrossed to a triple mutant male, the following 1,000 progeny are produced:

Wild type eyes, wings, and bristles:

90 females, 89 males

Wild type eyes and bristles, vestigial:

83 females, 98 males

Wild type eyes and wings, spineless:

37 females, 35 males

Wild type wings and bristles, blue eyes:

36 females, 34 males

Wild type wings, blue eyes, spineless:

92 females, 88 males

Wild type eyes, spineless, vestigial:

34 females, 39 males

Wild type bristles, vestigial, blue eyes:

33 females, 37 males

Blue eyes, spineless, vestigial:

90 females, 85 males

Calculate the map distance between blue eye and any linked genes. Show your work.

The progeny of a Drosphila female (heterozygous at three loci,y+y, ct+ct, w+w)

crossed to a wild-type male are listed as follows:

Females y+ ct+ w+ 2000

Males

y+ ct+ w 773

y ct w+ 782

y ct+ w+ 201

y+ ct w 209

y+ ct w+ 15

y ct+ w 16

y ctw 3

y+ ct+ w+ 1


a.) On which chromosome do these genes reside?

b.) What is the gene order and gene arrangement in the trihybridfemale parent?


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