At one time, membrane biologists thought that transport proteins might act by binding a solute molecule or ion on one side of the membrane and then diffusing across the membrane to release the solute molecule on the other side. We now know that this transverse carrier model is almost certainly wrong. Suggest two reasons that argue against such a model. One of your reasons should be based on our current understanding of membrane structure and the other on thermodynamic considerations.
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exergonic
hydrophobic
hydrophobic and hydrophilic
probable
endergonic
hydrophilic
improbable
Integral membrane proteins are embedded stably in the membrane and protrude from one or both sides based on their regions.
For a protein to traverse a membrane, movement of its region(s) through the interior of the membrane would be required, which would be highly and hence thermodynamically .
At one time, membrane biologists thought that transport proteins might act by binding a solute molecule or ion on one side of the membrane and then diffusing across the membrane to release the solute molecule on the other side. We now know that this transverse carrier model is almost certainly wrong. Suggest two reasons that argue against such a model. One of your reasons should be based on our current understanding of membrane structure and the other on thermodynamic considerations.
Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Not all terms will be used.
| Help Reset exergonic hydrophobic hydrophobic and hydrophilic probable endergonic hydrophilic improbable Integral membrane proteins are embedded stably in the membrane and protrude from one or both sides based on their regions. For a protein to traverse a membrane, movement of its region(s) through the interior of the membrane would be required, which would be highly and hence thermodynamically . |
