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Discussions Questions (4,2) Please help me Answer ALL to compare to my answers and Thank you with details & clarity!

3. Most regulatory proteins (activators or repressors) form dimers before they can bind. What are the advantages of dimerization of these proteins? Why do heterodimers bind different DNA sequences than homodimers? How might dimerization be used to regulate gene expression?

4. Architectural like HMG’s can bind to DNA and cause the DNA to bend at a sharp angle. Some of these protein promote transcription even though they do not contact the RNA Polymerase, GTF or any other regulatory protein. What is a plausible explanation for how these DNA bending proteins influence gene expression?

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Nelly Stracke
Nelly StrackeLv2
28 Sep 2019

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