Janeways's Immunology 9th edition Chapter 6 4. Fill-in-the-Blanks: Cell membrane-destined polypeptides are translocated to the lumen of the endoplasmic reticulum, which is intriguing because the MCH class I presented peptides are found in the _______. Further research revealed that presentation of cytosolic peptides is possible due to a family of ABC transporters, _______, that mediate the ATP-dependent transport of peptides into the lumen of the _______. This transporter complex has limited specificities for the transported peptides; for example, peptides are generally ______ amino acids in length and transport is biased in favor of _____ residues in the carboxyl terminus and against ______ residues within the first _______ amino-terminal residues.
Janeways's Immunology 9th edition Chapter 6 4. Fill-in-the-Blanks: Cell membrane-destined polypeptides are translocated to the lumen of the endoplasmic reticulum, which is intriguing because the MCH class I presented peptides are found in the _______. Further research revealed that presentation of cytosolic peptides is possible due to a family of ABC transporters, _______, that mediate the ATP-dependent transport of peptides into the lumen of the _______. This transporter complex has limited specificities for the transported peptides; for example, peptides are generally ______ amino acids in length and transport is biased in favor of _____ residues in the carboxyl terminus and against ______ residues within the first _______ amino-terminal residues.
