Question

1. A geneticist has obtained two true-breeding strains of mice,each homozygous for an independently discovered recessive mutationthat prevents the formation of hair on the body. One mutant strainis called naked, and the other is calledhairless. To determine whether the two mutations arealleles, the geneticist crossed naked andhairless mice with each other. All the offspring arephenotypically wild-type; (i.e., they have hairs all overtheir bodies). After crossing the wild-type F1, the geneticistobserves 115 wild-type mice and 85 mutant mice in the F2.
   1. (a) Determine the relationship between naked andhairless.
   2. (b) Explain the reasoning behind your answer to part (a).
   3. (c) What is the expected phenotypic Mendelian ratio withcorresponding phenotypes for F2

generation?

1. (d) Using proper and appropriate notation, indicate all thedifferent genotypes in the F2 that could be

wild-type; that could be naked; andthat could be hairless.