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FLOW OF GENETIC INFORMATION - TRANSCRIPTION & TRANSLATION

1. Describe/Explain the degeneracy of the genetic code. How does degeneracy impact the flow of genetic information?

2. Explain which of the following characteristics of DNA-dependent DNA synthesis (i.e. replication) is NOT the for DNA-dependent RNA synthesis?

(a) synthesis requires a template (b) requires a primer

(c) imitation involves recognition of DNA (d) synthesis is 5’ to 3’

3. Explain the stage of translation when an incoming tRNA has bound to the A-site on the ribosome. Describe/Explain the addition of amino acids to the growing polypeptide chain.

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Hubert Koch
Hubert KochLv2
28 Sep 2019

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Related questions

3. Complementary base pairing is an essential feature of DNA replication and transcription and translation. Explain how.

4. What’s the significance of the fact that operator and promoter overlap?

5. In which direction (3’?5’ or 5’?3’) does elongation of RNA occur?

6. In the genetic code, UUU and UUC both code for the same amino acid. What is this amino acid and what does this indicate about the genetic code?

7. Which part of a ribosome accepts a tRNA molecule that is attached to a growing polypeptide chain?

DNA synthesis: leading vs lagging strands during replication, Okazaki fragments, 5’ to 3’ direction vs 3’ to 5’ direction, meaning of ‘antiparallel’, role of DNA ligase, role of DNA polymerase

Transcription/translation, RNA/DNA, template strand vs non-template strand, introns vs exons

Relationship of DNA mutation to cancer.

Relationship of RNA to DNA, and RNA to proteins?

Meaning of semiconservative replication.

Codons (triplets) are part of what molecule?

Codons vs anticodons.

Functions of the different types of RNA.

Ribosome structure (including the E site, P site and A site).

Explain the stage of translation when an incoming tRNA has bound to the A-site on the ribosome. Describe/Explain the addition of amino acids to the growing polypeptide chain.

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