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How are virus particles assembled? Where do they get proteins for the nucleocapsid and proteins embedded in the envelope?

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Hubert Koch
Hubert KochLv2
28 Sep 2019

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Related questions

Understand the lifecycle steps for (-) RNA virus like influenza and for a retrovirus like HIV.

- How does the genome for each of these virus types get copied?

- How do the viral proteins for these virus types get made?

- How does the cell’s secretory pathway play a role in ensuring viral envelopes are studded with viral surface proteins?

- What role does this play in the generation of viral strain variation?

In this lab exercise you will watch animations about viruses and answer questions about them.

ANIMATION #2

Click on the link below to watch an animation by McGraw-Hill about the entry of a virus into an animal host cell:

http://highered.mcgraw-hill.com/sites/0072556781/student_view0/chapter18/animation_quiz_1.html

Answer the following questions about the animation:

1. Name the green molecules embedded in the envelope of the virus, or virion:

2. What do these molecules attach to on the host cell membrane?

3. What does the envelope of the virus fuse with in order to release the viral capsid into the host cell?

4. What is the innermost part of the virus that is released by the protein capsid into the cytoplasm of the host cell?

Proteins are common components of a cell. They can serve structural or enzymatic roles in the cell. Often they are associated with cell membranes. Differentiate between extrinsic and intrinsic proteins. Proteins that are embedded into the plasma membrane are often anchored via one of four methods. Define and describe each protein anchor type (10 points).

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