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28 Sep 2019
In his early work on the Citric Acid Cycle, Hans Krebs mademeasurements of oxygen consumption by suspensions of muscle cells.He found that addition of succinate, fumarate or malate to the cellsuspension stimulated oxygen consumption, and that the amount ofoxygen consumed was about 10-fold more than the amount needed forthe complete oxidation of the added compound. Moreover, thesuccinate, fumarate or malate was not consumed by the cellsuspension but was still detectable
at the end of the experiment. What is the correct interpretationof these observations?
In his early work on the Citric Acid Cycle, Hans Krebs mademeasurements of oxygen consumption by suspensions of muscle cells.He found that addition of succinate, fumarate or malate to the cellsuspension stimulated oxygen consumption, and that the amount ofoxygen consumed was about 10-fold more than the amount needed forthe complete oxidation of the added compound. Moreover, thesuccinate, fumarate or malate was not consumed by the cellsuspension but was still detectable
at the end of the experiment. What is the correct interpretationof these observations?
Nestor RutherfordLv2
28 Sep 2019
