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28 Sep 2019
Mitochondria Generating ATP
a) What would be the effect on ATP production of adding asubstance like 2,4-dinitrophenol(alprotonophore) that makes themitochondrial membrane leaky to protons?
b) Suppose that the gulcose supply to the cell is gratlyreduced. What would be the effect on CO2 procuction by themitochondrion?
c)Pretend that you are playing mitochondrial CSI. You find thatthe mitochondria has been poisoned and it smells distincly ofalmonds... Cyanide! Cyanide (CN-) poisons the electron transportchain by interfering with cytochrome C oxidase. Explain whathappends to the mitochondria when Cytochrome C oxidase is no longerable to function. (Hint: does it still form a prton gradient?why/how? Can it still make ATP? why/how?)
Mitochondria Generating ATP
a) What would be the effect on ATP production of adding asubstance like 2,4-dinitrophenol(alprotonophore) that makes themitochondrial membrane leaky to protons?
b) Suppose that the gulcose supply to the cell is gratlyreduced. What would be the effect on CO2 procuction by themitochondrion?
c)Pretend that you are playing mitochondrial CSI. You find thatthe mitochondria has been poisoned and it smells distincly ofalmonds... Cyanide! Cyanide (CN-) poisons the electron transportchain by interfering with cytochrome C oxidase. Explain whathappends to the mitochondria when Cytochrome C oxidase is no longerable to function. (Hint: does it still form a prton gradient?why/how? Can it still make ATP? why/how?)
Nestor RutherfordLv2
28 Sep 2019
