answer the following based upon a tripeptide sequence of thefollowing amino acids (one letter codes are given):
T L R
a) what is the overall charge on the tripeptide at physiologicalpH (pH 7.4)?
b) for each of the amino acids, is the side chain (R group)hydrophobic, polar but uncharged, positively charged, or negativelycharged at physiological pH?
T:
L:
R:
c) What is the overall charge of the tripeptide below pH1.0?
d) What ist he overall charge of the tripeptide at pH 12?
e) What type of intermolecular attractions could the side chainsof the amino acids make with the solvent (water) at pH 7.4? (Notethat these attractions are with water and not other aminoacids)
Option 1: ionic interactions
Option 2: hydrogen bonds
Option 3: hydrophobic interactions
f) if the tripeptide was disolved in a buffer that is pH 8.5,what would be the net charge on the most abundant chemicalspecies?
answer the following based upon a tripeptide sequence of thefollowing amino acids (one letter codes are given):
T L R
a) what is the overall charge on the tripeptide at physiologicalpH (pH 7.4)?
b) for each of the amino acids, is the side chain (R group)hydrophobic, polar but uncharged, positively charged, or negativelycharged at physiological pH?
T:
L:
R:
c) What is the overall charge of the tripeptide below pH1.0?
d) What ist he overall charge of the tripeptide at pH 12?
e) What type of intermolecular attractions could the side chainsof the amino acids make with the solvent (water) at pH 7.4? (Notethat these attractions are with water and not other aminoacids)
Option 1: ionic interactions
Option 2: hydrogen bonds
Option 3: hydrophobic interactions
f) if the tripeptide was disolved in a buffer that is pH 8.5,what would be the net charge on the most abundant chemicalspecies?
