1.) Proteins that make up the cytoskeleton play a key role in cellstructure and movement. Select the proteins below that you wouldconsider cytoskeletal proteins:
A. ubiquitin
B. kinases
C. tubulin
D. intermediate filaments
E. phosphatases
F. actin
2.) Actin or tubulin polymer growth/ disassembly is dependent onthe concenntration of monomer present in the cell. Polymer growthand disassembly can be discussed in terms of monomer on and offrates, respectively. At the critical concentration (Cc):
A. all monomer is degraded
B. momomer on rate > monomer off rate
C. monomer on rate < monomer off rate
D. monomer on rate = momomer off rate
3.) Microtubules are subject to dynamic instability. In fact, theregulation of these characteristic governs many cellular processessuch as chomosome segragation during mitosis. Choose the bestexplanation of the concept of dynamic instability.
A. This is the concept of GEF recruitment to microtubules to stimulategrowth and GAP recruitment to stimulate disassembly.
B. Microtubules require GTP to disassemble, GTP hydrolysis results inmicrotubule growth.
C. Actin filaments alternate between periods of rapid growth anddisassembly that is dependent on GTP binding.
D. Microtubules alternate between growth and disassembly. This isdependent on the presence of the GTP cap. Microtubules with a GTPcap are stable and favor growth, while loss of the GTP cap resultsin rapid disassembly.
3 separate questions. Thank you in advance!
1.) Proteins that make up the cytoskeleton play a key role in cellstructure and movement. Select the proteins below that you wouldconsider cytoskeletal proteins:
| A. | ubiquitin | |
| B. | kinases | |
| C. | tubulin | |
| D. | intermediate filaments | |
| E. | phosphatases | |
| F. | actin |
2.) Actin or tubulin polymer growth/ disassembly is dependent onthe concenntration of monomer present in the cell. Polymer growthand disassembly can be discussed in terms of monomer on and offrates, respectively. At the critical concentration (Cc):
| A. | all monomer is degraded | |
| B. | momomer on rate > monomer off rate | |
| C. | monomer on rate < monomer off rate | |
| D. | monomer on rate = momomer off rate |
3.) Microtubules are subject to dynamic instability. In fact, theregulation of these characteristic governs many cellular processessuch as chomosome segragation during mitosis. Choose the bestexplanation of the concept of dynamic instability.
| A. | This is the concept of GEF recruitment to microtubules to stimulategrowth and GAP recruitment to stimulate disassembly. | |
| B. | Microtubules require GTP to disassemble, GTP hydrolysis results inmicrotubule growth. | |
| C. | Actin filaments alternate between periods of rapid growth anddisassembly that is dependent on GTP binding. | |
| D. | Microtubules alternate between growth and disassembly. This isdependent on the presence of the GTP cap. Microtubules with a GTPcap are stable and favor growth, while loss of the GTP cap resultsin rapid disassembly. 3 separate questions. Thank you in advance! |
