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Phophofructokinase-1 (PFK-1) isan allosteric enzyme. Its activity is inhibited by:

Select one:

a. AMP

b. ATP

c. NAD+

d. glucose

e. All of the above

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When the AMP levelin the cell is ___________ (High/Low), it binds at an allostericsite on the glycolytic enzyme phosphofructokinase and __________(activates/inhibits) it.

Select one:

a. High; activates

b. High; inhibits

c. Low; activates

d. Low, inhibits

e. No effect

Question 19

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In glycolysis, fructose 1,6-bisphosphate is converted to twoproducts with a standard free-energy change (?Go') of +23.8 kJ/mol.Under what conditions (encountered in a normal cell) will thefree-energy change (?G') be negative, enabling the reaction toproceed to the right?

Select one:

a. If the concentrations ofthe two products are high relative to that of fructose1,6-bisphosphate.

b. The reaction will not goto the right spontaneously under any conditions because the G ispositive.

c. Under standard conditions,enough energy is released to drive the reaction to the right.

d. When there is a highconcentration of fructose 1,6-bisphosphate relative to theconcentration of products.

e. When there is a highconcentration of products relative to the concentration of fructose1,6-bisphosphate.