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28 Sep 2019
Brown fat, which is common in human infants, is specialized for the production of heat to keep the infant warm. Mitochondria in brown fat produce a protein known as thermogenin (UCP1) that associateswith the inner mitochondrial membrane and rapidly transports H+ from the intermembrane space back to the mitochondrial matrix, thus bypassing the ATP Synthase complex. Mitochondrial electron transport occurs normally in brown fat. It has been shown that thermogenin is necessary for heat production by brown fat. Explain how thermogenin might cause increased heat production by brown fat?
Brown fat, which is common in human infants, is specialized for the production of heat to keep the infant warm. Mitochondria in brown fat produce a protein known as thermogenin (UCP1) that associateswith the inner mitochondrial membrane and rapidly transports H+ from the intermembrane space back to the mitochondrial matrix, thus bypassing the ATP Synthase complex. Mitochondrial electron transport occurs normally in brown fat. It has been shown that thermogenin is necessary for heat production by brown fat. Explain how thermogenin might cause increased heat production by brown fat?
Reid WolffLv2
28 Sep 2019
