1. Juanâs family has a history of sickle cell disease. Hisfather died of sickle cell disease complications when Juan was sixyears old. He remembers his father being in great pain. Juanmarries Gina. Ginaâs maternal grandmother and paternal grandfatherhad sickle cell disease, but neither of her parents has thedisease. Juan does not want to have children because he isconvinced they will have sickle cell disease. Gina is not so sure.They have come to you for advice about having whether or not tohave children. Based on your calculations of the probability oftheir child getting sickle cell disease, what is your advice? Showyour calculations and explain your reasoning for your response. Itmay be helpful for you to draw pedigrees and possible Punnettsquares for both Juanâs and Ginaâs families.
1. Juanâs family has a history of sickle cell disease. Hisfather died of sickle cell disease complications when Juan was sixyears old. He remembers his father being in great pain. Juanmarries Gina. Ginaâs maternal grandmother and paternal grandfatherhad sickle cell disease, but neither of her parents has thedisease. Juan does not want to have children because he isconvinced they will have sickle cell disease. Gina is not so sure.They have come to you for advice about having whether or not tohave children. Based on your calculations of the probability oftheir child getting sickle cell disease, what is your advice? Showyour calculations and explain your reasoning for your response. Itmay be helpful for you to draw pedigrees and possible Punnettsquares for both Juanâs and Ginaâs families.
