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Finding possible amino acid sequences:

A polypeptide contains 100 amino acids. How many possible aminoacid sequences are there for this polypeptide?

I know the answer to be 20, but I'm not sure how this wasderived. Thank you for your help.

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Nestor Rutherford
Nestor RutherfordLv2
28 Sep 2019
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Related questions

I do not really know how to answer this. Any help would beappreciated, thank you. a) Describe the three steps in eukaryoticmRNA processing. What is the importance of each processing step? b)How many different mRNA sequences can encode a polypeptide chainwith the amino acid sequence Met-Leu-Arg ( include just the codingpart of the mRNA, but don't forget the stop codon!)? c) Pleaseexplain the functions of the A,P,and E aminoacyl-tRNA binding sitesof the ribosome.

Amino Acid Sequence Comparisons
Assignment Goal: To use the Internet-based site ExPASy program SIM to align two amino acid sequences. Knowing the sources of these sequences will allow one to determine the mutation and potential cause of a human disease.
Assignment: Access the ExPASy site at http://www.expasy.ch/tools/sim-prot.html
Copy and paste each of the following sequences into the “Sequence” text boxes in SIM.
Person 1/Sequence 1:
MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSGDDSVFAHDLLPPAPPSSGGSRT
Person 2/Sequence 2:
MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYRVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLL
GACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT
Click the “User entered sequence” button for each sequence entered.
Submit the sequences for comparison.
25. DO YOU SEE ANY DIFFERENCES BETWEEN THE TWO AMINO ACID SEQUENCES? (Look for the absence of an asterisk, which indicates the same amino acid in both sequences.)
26. IF YOU SAW DIFFERENCES, WHAT WERE THEY?
Return to the BLAST home page (http://blast.ncbi.nlm.nih.gov/Blast.cgi). Run a PROTEIN BLAST search to identify the polypeptide which you have been analyzing. (You may use either sequence.)
27. WHAT GENE ENCODES FOR THE POLYPEPTIDE YOU WERE ANALYZING?
Click on “Description”, then choose “Gene” under “Related Information” to answer the following two questions.
28. WHAT IS THE FUNCTION OF THIS PROTEIN?
29. WHAT HUMAN DISEASE IS CAUSED BY A MUTATION IN THIS GENE?


I really just need help on 27-29! Thank you!

2. You compare the amino acid sequences of an enzyme from yeast and human cells whose function is to break apart the disaccharide fructose. The amino acid sequences of these two enzymes are quite different. However, when you examine the 3-dimensional conformation of these two enzymes, you find that they have almost identical conformations. How is it possible for two proteins to have very different amino acid sequences and still fold the same way? (Hint: in your answer, consider the properties of the non-identical amino acids in the two enzymes). [6 points]

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