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In humans, the condition for normal blood clotting dominates the condition for non-clotting or hemophilia. Both alleles are linked to the X chromosomes. A male hemophiliac marries a women who is a carrier for this condition. In this respect, a carrier is a women who has an allele for normal blood clotting and an allele for hemophilia.

a. What are the chances that if they have a male child he will be normal for blood clotting?

b. A male who has normal blood clotting marries a women who is a carrier for this condition. What are the chances that if they have a male child he will be normal for blood clotting?

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Hubert Koch
Hubert KochLv2
28 Sep 2019
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Related questions

Ben has hemophilia. his parents both are normal for blood clotting. in his family history, he knows his grandfather and great uncle on his mother's side are both hemophilic. None of the female relatives are known to have hemophilia.

a) what is the mode of inheritence for hemophilia?

b) what is Ben's mother's genotype?

c) what is ben's father's geotype?

d) ben's sister is normal for blood clotting. What is the chance she is a carrier?

e) if Ben marries connie, who has normal blood clotting but who's father is a hemophiliac, what are the expected phenotype and genotype ratios of the offspring (state in % of sons and daughters)

Show your work using punnet squares

The following question is a sex-linked trait. Review the patterns of inheritance of sex-linked traits before answering the following questions. Make sure to indicate chromosomes and alleles in your answers when necessary.

Hemophilia is a caused by a recessive mutation found on the X chromosome in humans. The recessive allele (Xh) is associated with abnormal blood clotting (hemophilia), while the dominant allele (XN) causes normal blood clotting.

A man with normal blood clotting and woman who is heterozygous are going to have a child. What is the probability of an offspring who is a carrier of hemophilia, and if so, the sex(es) of the offspring?

A. Chances are 25% of a son who is a carrier

B. There is no chance of an offspring who is a carrier

C. Chances are 50% of either a son or a daughter who is a carrier

D. All offspring, male or female, will be carriers

E. Chances are 1 in 4 of a daughter who is a carrier

2. Two fruit flies, one with red eyes and one with white eyes mate and have an offspring with white eyes. Having red eyes is a dominant trait (R) while white eyes (w) is recessive. Based on this information, what must be the genotypes of the parental white-eyed fruit fly and the parental red-eyed fruit fly?

A. Red-Eyed fruit fly: Rw

White-eyed fruit fly: ww

B. Red-Eyed fruit fly: RR

White-eyed fruit fly: wR

C. Red-Eyed fruit fly: R

White-eyed fruit fly: w

D. Red-Eyed fruit fly: rr

White-eyed fruit fly: wr

E. Red-Eyed fruit fly: RR

White-eyed fruit fly: ww

Practice Problems, p. 157.
1. Hemophilia is a sex-linked trait where XH gives normal blood clotting and is dominant to the hemophilia allele Xh. Males that are XHY are normal but males that are XhY are hemophiliacs. For women: XHXH are normal
(unaffected); XHXh are normal but carry the allele (carriers); XhXh have hemophilia (are affected).

aii. What is the genotype for Brad with normal blood clotting whose father had hemophilia?

bi. Cross Angelina and Brad. What are Angelina's possible gametes?

bii. Cross Angelina and Brad. What are Brad's possible gametes?

c. What is the probability that a mating between these two individuals will produce a child, regardless of sex, that has hemophilia? (Give a percentage.)

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