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What is the relative gene order, and the map distance between these genes, based on thefollowing results from this three point mapping cross:

a B d 404

A b D 395

A B d 210

a b D 195

a B D 15

A b d 19

a b d 154

A B D 139

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Tod Thiel
Tod ThielLv2
28 Sep 2019

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Related questions

ANSWER ALL the PARTS you can

PART1 Alleles are considered linked if recombination is less than 50% in:

a) a Px P Fl cross

b) an F1 x F1F2 cross

c) an F2 x F2F3 cross

d) an Fl x homozygous recessive cross

e) any F2 progeny x homozygous recessive cross 1.

PART2 If two loci A/a B/b are 9 map units apart, and an Ab/aB individual is testcrossed,

a) There will be 9% AB individuals

b)There will be 91% Ab individuals

c) There will be 4.5% ab individuals

d) There will be 91% recombination individuals

If two genes a and b show 50% recombination genes a and c show 35% recombination, and genes b and show 32% recombination, then

a) Genes a and b are on the same chromosome, and 50 m.u. apart

b) Genes a and b are on different chromosomes

c)Genes a and b are on the same chromosome, and 67 map units apart

d) One cannot tell if genes a and b are on the same or different chromosomes from given data.

PART4 If two genes a and b are 8.3 m.u. a part, one expects to find

a) 8.3% recombinant gametes from a double heterozygous parent

b) 91.7% recombinant gametes from a double heterozygous parent

c) A chiasma between the a and b loci in 8.3% of the meiosis

d) A chiasma between the a and b loci in 91.7% of the meiosis.

PART5 Map distances are most accurate when genes are closely linked because as genes become further apart,

a) They always show independent assortment

b)The chance of multiple crossovers increases

c) They no longer recombine

d) There is chiasma interference

PART6 In a three-point testcross, the most frequent classes of progeny were ABc and abC. The less frequent classes of progeny were AbC and aBc. Which gene is in the middle?

a) Aa

b) B/b

c)C/c

d) It is not possible to tell from just these data

PART7 In a three-point testcross with 100 progeny, there were 16 single crossovers between genes A and B, 29 single crossovers between genes B and C, and 4 double crossovers. The correct gene order was determined to be A-B-C. What is the map distance between A and B?

a) 20%

b) 0.2 m.u

c) 20 m.u.

d) 16 m.u.

e) 29 m.u.

f) 16%

QUESTION 5

When determining the relative genetic distance between two genes, why is dihybrid back-cross preferable over traditional dihybrid cross?

a.

9:3:3:1 phenotypic ratio is easier to work with than 1:1:1:1 ratio.
b.

Genotypes of the offspring can be determined based on their phenotype.
c.

Unlike the traditional dihybrid cross, dihybrid back-cross produces all possible combinations of genotypes.
d.

All of the above

Why do we map genes?

a.

To understand how genes interact with each other
b.

Comparative genomics analysis
c.

To determine the genotype of an organism
d.

All of the above

1. (10 points) You have a strain of fruit flies that are black in colour (b) instead of the usual tan, have shortened wings (sw) relative to wild type, and pinkish eyes (p) instead of red. You cross b. sw. p females to wild type males and all the F1 are wild type.

Then you cross the F1 females to males from the original strain รขย€ย“ b. sw. p. You obtain the following number and phenotypes of F2:

b sw p : 422

b+ sw+ p+: 403

b sw+ p: 63

b+ sw p+: 52

b sw p+: 31

b+sw+ p: 24

b+ sw p : 3

b sw+ p+: 2

a) Determine the correct gene order and explain how you know. (1 point)

b) Calculate map distances between all three pairs of genes, if appropriate (6 points)

c) Draw a map showing the arrangement of the genes (1 point)

d) Calculate the interference if any, and explain in one or two sentences what interference is (use your own words) (2 points)

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