Are the following genetic mutation positive for the 3 characteristics listed below - Phenylketonuria (PKU), Smith-Lemli-Opitz syndrome (SLOS), Alzheimerâs disease, Sickle cell anemia?
1. It is inherited (at least in some individuals or families) as a single-gene disorder (this means that a disorder where many cases are due to a mix of multiple contributing genes and environmental factors, such as heart disease or Alzheimerâs, could still be chosen if you focus on those instances with a single-gene cause)
2. It demonstrates at least one non-Mendelian characteristic (incomplete penetrance, variable expressivity, sex inflence, sex limited multiple alleles, or incomplete dominance) in its inheritance pattern
3. It is caused by mutations in a gene that has been identified and characterized.
Are the following genetic mutation positive for the 3 characteristics listed below - Phenylketonuria (PKU), Smith-Lemli-Opitz syndrome (SLOS), Alzheimerâs disease, Sickle cell anemia?
1. It is inherited (at least in some individuals or families) as a single-gene disorder (this means that a disorder where many cases are due to a mix of multiple contributing genes and environmental factors, such as heart disease or Alzheimerâs, could still be chosen if you focus on those instances with a single-gene cause)
2. It demonstrates at least one non-Mendelian characteristic (incomplete penetrance, variable expressivity, sex inflence, sex limited multiple alleles, or incomplete dominance) in its inheritance pattern
3. It is caused by mutations in a gene that has been identified and characterized.
