If someone can please help me, I have answers for this assignment. I just want to make sure they are correct...
1. A 12-year-old male whose family recently emigrated from eastern Europe presents to the emergency room with a fever of 103.5F, a swollen neck, difficulty breathing, and grayish-white membranes in the oropharynx. Cultures were taken from the pharynx and the bacteria were found to be Gram-positive rods with metachromatic granules. The toxin produced by this bacterium has which of the following mechanism of action?
A. Pertussis toxin inhibits the G protein Gai via ADP Ribosylation
B. Overactivates guanylate cyclase
C. Inactivates the 60S ribosomal subunit
D. Inactivates elongation factor 2
E. Cleaves SNARE proteins
2. A 6-year-old male who recently immigrated to the United States from Asia is admitted to the hospital with dyspnea. Physical exam reveals a gray pseudomembrane in the patient's oropharynx along with lymphadenopathy. The patient develops myocarditis and expires on hospital day 5. Which of the following would have prevented this patient's initial infection?
A. Increased CD4+ T cell count
B. Secretory IgA against viral proteins
C. Increased IgM preventing bacterial invasion
D. Circulating IgG against AB exotoxin
E. Improved IgE release from mast cells
3. A 3-year-old male is brought to the ER with a sore throat and fever. Examination of the pharynx reveals a dark, inflammatory exudate. Cysteine-tellurite agar culture produces black, iridescent colonies. Microscopic features of the causal organism most likely include which of the following?
A. Serpentine growth patterns
B. Metachromic granules
C. Lancet-shape
D. Long, branching filaments
E. Kidney-bean shaped rod
4.What treatment would you recommend for the above patients who did not expire?
A. Erythromycin and/or Penicillin
B. Kanamycin
C. Ampicillin
D. Fluid and Bedrest
If someone can please help me, I have answers for this assignment. I just want to make sure they are correct...
1. A 12-year-old male whose family recently emigrated from eastern Europe presents to the emergency room with a fever of 103.5F, a swollen neck, difficulty breathing, and grayish-white membranes in the oropharynx. Cultures were taken from the pharynx and the bacteria were found to be Gram-positive rods with metachromatic granules. The toxin produced by this bacterium has which of the following mechanism of action?
A. Pertussis toxin inhibits the G protein Gai via ADP Ribosylation
B. Overactivates guanylate cyclase
C. Inactivates the 60S ribosomal subunit
D. Inactivates elongation factor 2
E. Cleaves SNARE proteins
2. A 6-year-old male who recently immigrated to the United States from Asia is admitted to the hospital with dyspnea. Physical exam reveals a gray pseudomembrane in the patient's oropharynx along with lymphadenopathy. The patient develops myocarditis and expires on hospital day 5. Which of the following would have prevented this patient's initial infection?
A. Increased CD4+ T cell count
B. Secretory IgA against viral proteins
C. Increased IgM preventing bacterial invasion
D. Circulating IgG against AB exotoxin
E. Improved IgE release from mast cells
3. A 3-year-old male is brought to the ER with a sore throat and fever. Examination of the pharynx reveals a dark, inflammatory exudate. Cysteine-tellurite agar culture produces black, iridescent colonies. Microscopic features of the causal organism most likely include which of the following?
A. Serpentine growth patterns
B. Metachromic granules
C. Lancet-shape
D. Long, branching filaments
E. Kidney-bean shaped rod
4.What treatment would you recommend for the above patients who did not expire?
A. Erythromycin and/or Penicillin
B. Kanamycin
C. Ampicillin
D. Fluid and Bedrest
