Description
Both Immunoglobulins and the proteins of the MHC complex are capable of recognizing a very broad range of proteins or peptides associated with pathogens. Their methods of establishing this wide repertoire of recognition is established at the genetic level, but have no similarities in the processes.
Instructions
Describe the genes of both these effectors, characterizing the steps in the generation of this diversity in Immunoglobulins. Describe the inheritance of MHC genes and how these genes are expressed and regulated. You should include your explanation of polygeny and polymorphism as it relates to the MHC haplotype of an individual, and also include explanation of affinity maturation and somatic hypermutation with your description of immunoglobulins.
Description
Both Immunoglobulins and the proteins of the MHC complex are capable of recognizing a very broad range of proteins or peptides associated with pathogens. Their methods of establishing this wide repertoire of recognition is established at the genetic level, but have no similarities in the processes.
Instructions
Describe the genes of both these effectors, characterizing the steps in the generation of this diversity in Immunoglobulins. Describe the inheritance of MHC genes and how these genes are expressed and regulated. You should include your explanation of polygeny and polymorphism as it relates to the MHC haplotype of an individual, and also include explanation of affinity maturation and somatic hypermutation with your description of immunoglobulins.
