Fill in the blanks in the following paragraph using words from the word bank below. Not all words will be used, and some may be used more than once.
Like T cells, B cells require multiple signals for activation. Antigen binding to the B cell antigen __________provides one signal, while antigen-specific effector ________ provide the other signals. The requirement for multiple signals to activate either a T cell or a B cell helps to prevent _______ and dangerous activation of _________ , including __________ _________. Most of the proteins involved in cellâcell recognition and antigen recognition in the immune system, including _________ , TCRs, and _______ proteins, as well as various co-receptors, belong to the ancient Ig superfamily. This superfamily is thought to have evolved from a primordial gene encoding a single Ig- like _______ . The mechanisms for diversifying antibodies and T cell receptors by recombining gene segments may have arisen when a _________ inserted into an exon of a gene encoding an Ig family member.
receptors (BCRs) helper T cells killer T cells
inappropriate appropriate monocytes
lymphocytes self-reactive non-self-reactive
antibodies IPR MHC
domain transposon retrovirus
Fill in the blanks in the following paragraph using words from the word bank below. Not all words will be used, and some may be used more than once.
Like T cells, B cells require multiple signals for activation. Antigen binding to the B cell antigen __________provides one signal, while antigen-specific effector ________ provide the other signals. The requirement for multiple signals to activate either a T cell or a B cell helps to prevent _______ and dangerous activation of _________ , including __________ _________. Most of the proteins involved in cellâcell recognition and antigen recognition in the immune system, including _________ , TCRs, and _______ proteins, as well as various co-receptors, belong to the ancient Ig superfamily. This superfamily is thought to have evolved from a primordial gene encoding a single Ig- like _______ . The mechanisms for diversifying antibodies and T cell receptors by recombining gene segments may have arisen when a _________ inserted into an exon of a gene encoding an Ig family member.
receptors (BCRs) helper T cells killer T cells
inappropriate appropriate monocytes
lymphocytes self-reactive non-self-reactive
antibodies IPR MHC
domain transposon retrovirus
