What chemical groups are found at the ends of DNA or RNA molecules? What chemical groups are found at the ends of polypeptide molecules? How are the ends or RNA molecules related to the ends of polypeptide molecules that they encode?

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Collen VonLv2

28 Sep 2019

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7) Describe how eukaryotic cells replicate the ends of linear DNA molecules without losing any important information.

8) List TWO differences between DNA and RNA and explain how they related to the way the two molecules are treated by the cell.

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The DNA of bacteriophage l is a linear double-stranded molecule that has complementary single-stranded ends. These molecules can form closed circular molecules when two âcohesiveâ ends on the same molecule join, and they can form linear dimers, trimers, or longer molecules when sites on different molecules are joined.

a) What conditions should be chosen to ensure that l phage DNA molecules form closed circular monomers, as opposed to dimers, trimers, etc?

b) Under certain, l phage DNA molecules are infective. When a very low concentration of l phage DNA is incubated with DNA polymerase I and the four deoxyribonucleoside triphosphates, the infectious activity of l phage DNA is destroyed. Brief treatment of l phage DNA with bacterial exonuclease III, an enzyme that removes 5â-mononucleotides from the 3â-ends of double-stranded DNA molecules, also destroys infectivity, but subsequent treatment of the DNA with DNA polymerase and nucleotide substrates can restore infectivity. What does this tell you about the structure of the cohesive ends of the DNA? Explain the effects of the two enzymes.

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Which of the following is correct about DNA replication? A. Replication begins from one end of the molecule, and ends at the other end. B. A type of RNA polymerase is the enzyme that lays down the first nucleotide of the daughter strand. C. Replication occurs in one chromosome at a time. D. DNA polymerase III and the primase have opposite directions of functions. E. At the end of replication, two DNA molecules are present- the original molecule, and a newly synthesized DNA molecule.

rosewoodchuck649

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What chemical groups are found at the ends of DNA or RNA molecules? What chemical groups are found at the ends of polypeptide molecules? How are the ends or RNA molecules related to the ends of polypeptide molecules that they encode?

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