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Membrane proteins tend to diffuse 3 to 30 times slower than proteins in the cytosol. Researchers are vey interested in knowing why membrane proteins diffuse slower than expected. Interestingly, purified membrane proteins incorporated into synthetic lipid bilayers diffuse crazy fast relative to the same protein in a native, biological membrane. What do you think explains the difference?

Shockingly, even lipids diffuse more slowly in biological membranes than in synthetic bilayers. What might be the cause of this strange behavior?

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Jean Keeling
Jean KeelingLv2
28 Sep 2019

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