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DNA polymerases are not able to prime replication, yet primase and other RNA polymerases can. Some geneticists have speculated that the inability of DNA polymerase to prime replication is due to its proofreading function. This hypothesis argues that proofreading is essential for the faithful transmission of genetic information and that, because DNA polymerases have evolved the ability to proofread, they cannot prime DNA synthesis. Explain why proofreading and priming functions in the same enzyme might be incompatible.
DNA polymerases are not able to prime replication, yet primase and other RNA polymerases can. Some geneticists have speculated that the inability of DNA polymerase to prime replication is due to its proofreading function. This hypothesis argues that proofreading is essential for the faithful transmission of genetic information and that, because DNA polymerases have evolved the ability to proofread, they cannot prime DNA synthesis. Explain why proofreading and priming functions in the same enzyme might be incompatible.
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aishkadao123Lv10
17 Dec 2023
Trinidad TremblayLv2
28 Sep 2019
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