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1. Explain the fundamental differences between up-regulation anddown-regulation of gene expression.

2. What is basal level gene expression, and why does ithappen?

3. A number of different mutations in the HBB gene can causethallassemia, a disease characterized by various levels of anemia.Many of these mutations occur within introns or in upstreamnoncoding sequences. Explain why mutations in these regions oftenlead to severe diseases, although they may not directly alter thecoding regions of the gene.

4. What might be two means an eukaryotic cell might use to stopthe movement of simple transposons in its genome?

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Hubert Koch
Hubert KochLv2
28 Sep 2019

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