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29 Sep 2019
The following sequence encodes the active site of an enzyme from Candida albicans. Mutagenic studies have shown that these exact four residues are essential for enzymatic function.
Glu Leu Gln Arg
GAG CTA CAA AGA
(a) List each of the possible synonymous mutations that could occur in the leucine codon. (2 marks)
(b) Suggest a base substitution in the glutamine codon that would truncate the encoded protein. What is the name of the codon created? (2 marks)
(c) Indicate a transversion that could occur in the arginine codon while still retaining function of the enzyme. (1 mark)
The following sequence encodes the active site of an enzyme from Candida albicans. Mutagenic studies have shown that these exact four residues are essential for enzymatic function.
Glu Leu Gln Arg
GAG CTA CAA AGA
(a) List each of the possible synonymous mutations that could occur in the leucine codon. (2 marks)
(b) Suggest a base substitution in the glutamine codon that would truncate the encoded protein. What is the name of the codon created? (2 marks)
(c) Indicate a transversion that could occur in the arginine codon while still retaining function of the enzyme. (1 mark)
Patrina SchowalterLv2
29 Sep 2019
