Which of the following would not be found near the 3' end of a mature eukaryotic mRNA?
A. Terminator sequences
B.poly-A-tail
C.UTR
D Stop codon
If you isolate a pancreatic cancer cell from a patient, which of the following would you be most likely to NOT discover?
a.You could see a different shape of the tumor cell as compared to a wild type pancreatic cell.
b. The cancer cell could have the ability to grow uncontrollably,unlike a normal pancreatic cell from the same patient.
c.The chromosome in the cancer cell could have the exact same DNA sequence as those from a wild type pancreatic cell from the same patient.
Which of the following would not be found near the 3' end of a mature eukaryotic mRNA?
A. Terminator sequences B.poly-A-tail C.UTR D Stop codon
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Part B
Think about the DNA coding sequence of a gene. If an A were swapped for a T, what kind of mutation could it cause and why?
a) It could cause a frameshift nonsense or frameshift missense mutation because it would change the reading frame of the codon triplet. | ||||||||||||||||||||||||||||
b) It could cause a silent, missense, or nonsense mutation because those are the types that can be caused by a nucleotide-pair substitution like this one. | ||||||||||||||||||||||||||||
c) It could cause a nonsense mutation because the sequence would no longer be the same, so the protein would be shorter and non-functional. | ||||||||||||||||||||||||||||
d) It could cause a silent mutation because A and T are complementary to each other so it is not really a substitution mutation. Part C Why is a frameshift missense mutation more likely to have a severe effect on phenotype than a nucleotide-pair substitution missense mutation in the same protein?
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