Question

My disease is malaria

Pick a nanoparticle you described in a previousassignment. Describe some of the different ways this nanoparticlecould be functionalized to accumulate in your diseased tissue ofinterest. Would it be more beneficial to perform active or passivetargeting? If you were to perform active targeting, what are 3different tissue biomarkers you would try to target, and why? Whatsorts of targeting molecules would you put on the surface of yournanoparticle? What are your most important considerations whenpicking targeting molecules (size, charge, affinity, etc)? How doyou expect this active targeting to change your overallnanoparticle accumulation in your tissue? If you were to performpassive targeting, what physical properties of your nanoparticlewould you optimize, and why? How do you expect this passivetargeting to change your overall nanoparticle accumulation in yourtissue?