Question

1-An enzyme that generally requires an FAD prosthetic group iscalled a/an
___________________ when it lacks that prosthetic group.
a. holoenzyme
b. apoenzyme
c. cofactor
d. essential ion

2. Notice in question (above) that the enzyme pyruvatedehydrogenase requires
an NAD+ molecule in order to catalyze the “transition step”.Pyruvate
dehydrogenase [*Please mark all that apply.]
a. requires a prosthetic group.
b. requires a cosubstrate.
c. functions only as an apoenzyme.
d. requires a coenzyme.

3. A group of anti-fungal drugs called the nikkomycins bind to theactive site
enzymes that synthesize chitin for the fungal cell wall. When thesedrugs are
bound to the active site of these enzymes, the enzymes’ substratescannot bind
and chitin synthesis is inhibited. (The Journal of Antibiotics,Vol. XXXVIII No.
1).
The nikkomycins
a. are allosteric feedback inhibitors.
b. are prosthetic groups.
c. are competitive enzyme inhibitors.
d. are noncompetitive enzyme inhibitors.

4. The amino acid Ser can be synthesized from a 3-carbon moleculecalled
phosphoglycerate. This metabolic process is
a. anabolic
b. catabolic
c. degragatory
d. crazy

5. Which statements are TRUE? [*Mark all that apply.]
a. The complete oxidation of glucose, as shown below, is anendergonic
process.
C6H12O6 + 6O2 ? 6CO2 + 6H2O ?G = -686 kcal/mol
b. If a reaction occurs in which heat is lost and disorderincreases, the
reaction is spontaneous.
c. The addition of a phosphate group to glucose (as shown below) isan
exergonic process:
glucose + phosphate ? glucose-6-phosphate + H2O ?G = 3.3kcal/mol
d. The cellular synthesis of fatty acids by the addition of2-carbon units to an
elongating carbon chain is an anabolic process.

6. Both NADH and FADH2
a. are reduced prosthetic groups.
b. are reduced cosubstrates.
c. carry a hydride ion.
d. deliver there electrons to the electron transport chain.

7. Which one of the following has the greatest desire forelectrons?
a. NAD+
b. FAD
c. Cytochrome c
d. O2