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27 Jun 2018

Explain and report on:

(1) The physics underlying the propagation of action potential in myelinated vs. unmyelinated axons.

(2) The mechanism by which voltage gated ion channels sense and respond to changes in membrane electrical potential.

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Lelia Lubowitz
Lelia LubowitzLv2
28 Jun 2018

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Related questions

In order for Neurons to communicate, Resting Membrane Potential must CHANGE. Examples of changes in Membrane Potential included Graded Potentials and Action Potentials. In order for there to be a change in membrane potential, ions must move across the plasma membrane. There are THREE Primary types of Ion Channels: Passive (Leak) Channels, Voltage-gated Channels and Chemically-gated Channels.

DIRECTIONS

Indicate which voltage-gated channels are functioning during each phase of an Action Potential

Please help

29. The action potential


a. begins with the membrane’s increased permeability to potassium.

b. returns to resting when the sodium channels open.


c. can be triggered by opening of ligand gated Na and K channels.


d. involves voltage-gated Chloride channels in the membrane.


e. can be triggered by opening of voltage gated Na+ and K+ channels.

30. Which of the following is not a step in the propagation of action potentials?


a. Sufficient local inward current causes the axon to reach threshold.


b. Local depolarization/inward current spreads to adjacent axonal regions.


c. Adjacent regions eventually reach threshold and exhibit an action potential waveform.


d. Current/depolarization continue to spread directionally along the axon, repeating steps a–c

e. All of the above are steps contributing to the propagation of action potentials.

31. Which of the following is important for the unidirectional propagation of action potentials?

a. The voltage dependence of the sodium channels


b. The voltage dependence of the potassium channels


c. The presence of a refractory period at a location where an action potential has just fired

d. Sufficient “leakiness” of the axons, such that backward propagation of action potentials is prevented


e. The capacity of axons to function as perfect insulators and prevent current leakage and backpropagation

In order for Neurons to communicate, Resting Membrane Potential must CHANGE. Examples of changes in Membrane Potential included Graded Potentials and Action Potentials. In order for there to be a change in membrane potential, ions must move across the plasma membrane. There are THREE Primary types of Ion Channels: Passive (Leak) Channels, Voltage-gated Channels and Chemically-gated Channels.

DIRECTIONS

Select ONE type of Ion Channel and indicate whether that Ion Channel is MOST important for producing Resting Membrane Potential, Graded Potentials or Action Potentials. Provide detailed support for your choice.

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